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SDHB
Pengidentifikasi
Alias	SDHB, CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP, succinate dehydrogenase complex iron sulfur subunit B, MC2DN4
ID Eksternal	OMIM: 185470; MGI: 1914930; HomoloGene: 2255; GeneCards: SDHB; OMA:SDHB - orthologs
Lokasi gen (Manusia)
Kr.	Kromosom 1 (manusia)
Akhir	17,054,032 pb
Lokasi gen (Tikus)
Kr.	Kromosom 4 (tikus)
Akhir	140,706,504 pb
Pola ekspresi RNA
	Ekspresi tertinggi di
	left ventricle; ; apex of heart; ; Otot gastrocnemius; ; muscle of thigh; ; mucosa of transverse colon; ; right ventricle; ; right auricle of heart; ; right lobe of liver; ; Otot vastus lateralis; ; Otot biceps brachii;
	Ekspresi tertinggi di
	right ventricle; ; myocardium of ventricle; ; digastric muscle; ; interventricular septum; ; plantaris muscle; ; Otot sternokleidomastoid; ; Otot jantung; ; soleus muscle; ; Diafragma; ; cardiac muscle tissue of left ventricle;
	Referensi data ekspresi selengkapnya
	n/a
Ontologi gen
Fungsi molekuler	ubiquinone binding; iron-sulfur cluster binding; metal ion binding; succinate dehydrogenase (ubiquinone) activity; Ikatan protein plasma; oxidoreductase activity; electron transfer activity; 2 iron, 2 sulfur cluster binding; 3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding;
Komponen seluler	membran; membran sel; nucleoplasm; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone); mitochondrial inner membrane; mitokondria; mitochondrial membranes; respiratory chain complex II;
Proses biologis	succinate metabolic process; aerobic dissimilation; Siklus asam sitrat; respiratory electron transport chain; Rantai transpor elektron;
	Sumber:Amigo / QuickGO
Ortologi
	6390
	67680
	ENSG00000117118
	ENSMUSG00000009863
	P21912
	Q9CQA3
	NM_003000
	NM_023374; NM_001355515
	NP_002991
	NP_075863; NP_001342444
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

SDHB adalah berkas genetik pada kromosom 1 lokasi 1p36.1-p35 dengan ekspresi genetik berupa protein sub-unit B dari suksinat dehidrogenase. Sub-unit B terdiri dari 3 kluster yang kaya akan sisteina. Mutasi pada gen akan menyebabkan paraganglioma dan feokromositoma, disfungsi mitokondria dan tumorigenesis.^[5]

Referensi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000117118 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000009863 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ (Inggris) "SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-11-05.

Artikel bertopik gen ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000117118 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000009863 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] (Inggris) "SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-11-05.

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l b s Oxidoreductases: CH–CH oxidoreductases (EC 1.3)
1.3.1: NAD/NADP acceptor	Enoyl-acyl carrier protein reductase/Enoyl ACP reductase 7-Dehydrocholesterol reductase Biliverdin reductase 2,4 Dienoyl-CoA reductase Dihydroxymethyloxo-tetrahydroquinoline dehydrogenase
1.3.3: Oxygen acceptor	Dihydroorotate dehydrogenase Coproporphyrinogen III oxidase Protoporphyrinogen oxidase Bilirubin oxidase Acyl-CoA oxidase Dihydrouracil oxidase Tetrahydroberberine oxidase Secologanin synthase Tryptophan alpha,beta-oxidase Pyrroloquinoline-quinone synthase L-galactonolactone oxidase
1.3.5: Quinone	Succinate dehydrogenase SDHA SDHB SDHC SDHD
1.3.99: Other acceptors	Fumarate reductase Butyryl-CoA dehydrogenase Acyl CoA dehydrogenase ACADSB ACADS 5α-reductase SRD5A1 SRD5A2 SRD5A3 Glutaryl-CoA dehydrogenase Isovaleryl coenzyme A dehydrogenase 3-oxo-5beta-steroid 4-dehydrogenase

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SDHB

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